Seacoast Region Vacations from $340

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Your Seacoast Region Vacation

Book a vacation package to Seacoast Region and make planning your adventure easy. With the finer details taken care of before you leave, you can focus on enjoying every second in this wonderful destination. With so many things to explore on a trip to Seacoast Region, it can be hard to know where to start. Kick off your journey in Portsmouth at Water Country and Kittery Premium Outlets — two popular attractions here. Another city worthy of a spot on your itinerary is Rochester. Be sure not to miss The Children's Museum of New Hampshire and Rochester Opera House. If you're ready to stop dreaming and start traveling, Expedia will help turn your Seacoast Region vacation into a reality.

The Latest Seacoast Region vacation packages

Price found within the past 48 hours. Click for updated prices.
Boston Lodge and Suites
Boston Harbor Hotel
The Revolution Hotel
Lakeside Inn
YOTEL Boston
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Where to stay in Seacoast Region

Find the best Seacoast Region areas and neighborhoods for the activities you enjoy most. Learn more about Seacoast Region

Discover the most popular places to visit in Seacoast Region

Seacoast Region Hotel Deals

Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

3 out of 5
100 High St, Portsmouth, NH
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $216 total per night from Oct 19 to Oct 20
$216 total
Oct 19 - Oct 20
Total with taxes and fees
8.4/10 Very Good! (114 reviews)
"I first had the handicapped room but it was dark and depressing. The beds were practically on the floor and way too soft. There was no chair except a desk chair and seems like a very stark and dark room I moved to a standard room which is wonderful! Far more cozy. The handicapped rooms could be far ..."

Reviewed on Sep 27, 2025

Hilton Garden Inn Portsmouth Downtown
Ashworth by the Sea

Ashworth by the Sea

3 out of 5
295 Ocean Blvd, Hampton, NH
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $176 total per night from Oct 13 to Oct 14
$176 total
Oct 13 - Oct 14
Total with taxes and fees
8/10 Very Good! (1,284 reviews)
"Area was awesome, Beach chairs and bikes for free check out was great. Hotel was a bit dated. Pool area needs work. Staff was very engaging."

Reviewed on Sep 24, 2025

Ashworth by the Sea
Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

3 out of 5
23 Portwalk Pl, Portsmouth, NH
Fully refundableReserve now, pay when you stay
$212 nightly
The price is $230 total per night from Oct 19 to Oct 20
$230 total
Oct 19 - Oct 20
Total with taxes and fees
9.4/10 Exceptional! (1,051 reviews)
"Dan at the front desk was awesome. Made our trip that much better."

Reviewed on Sep 27, 2025

Hampton Inn & Suites Portsmouth Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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